Article
Genetic interaction between ribosome biogenesis and inositol polyphosphate metabolism in Saccharomyces cerevisiae.
Bioscience, biotechnology, and biochemistry - 1 Feb 2009
Horigome Chihiro, Ikeda Ryo, Okada Takafumi, Takenami Kazuhiko, Mizuta Keiko
Abstract excerpt
Rrs1 has an essential role in 60S ribosomal subunit assembly in Saccharomyces cerevisiae. We isolated a temperature-sensitive kcs1 mutant that suppresses the cold sensitivity of rrs1-1. The kcs1 allele, resulting in truncation of inositol 6 phosphate kinase domain, and kcs1 disruption suppress a...
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