Article
The C-terminus of the P22 tailspike protein acts as an independent oligomerization domain for monomeric proteins.
The Biochemical journal - 1 May 2009
Webber Tawnya, Gurung Sarsati, Saul Justin, Baker Trenton, Spatara Michelle, Freyer Matthew, Robinson Anne Skaja, Gage Matthew J
Abstract excerpt
TSP (P22 tailspike protein) is a well-established model system for studying the folding and assembly of oligomeric proteins, and previous studies have documented both in vivo and in vitro folding intermediates using this protein. Especially important is the C-terminus of TSP, which plays a critical role in the assembly and maturation of the protrimer intermediate to its final trimeric form. In the present study,...
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