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Article

Dimerization of ERp29, a PDI-like protein, is essential for its diverse functions.

Molecular biology of the cell - 1 Apr 2007

Rainey-Barger Emily K, Mkrtchian Souren, Tsai Billy

Abstract excerpt

Protein disulfide isomerase (PDI)-like proteins act as oxido-reductases and chaperones in the endoplasmic reticulum (ER). How oligomerization of the PDI-like proteins control these activities is unknown. Here we show that dimerization of ERp29, a PDI-like protein, regulates its protein unfolding and escort activities. We have demonstrated previously that ERp29 induces the local unfolding of polyomavirus in the...

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Identifiers

PMID: 17267685
DOI: 10.1091/mbc.e06-11-1004
PMCID: PMC1838973

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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