Article
Generation of envelope and defective interfering RNA mutants of tomato spotted wilt virus by mechanical passage.
The Journal of general virology - 1 Oct 1991
Resende R de O, de Haan P, de Avila A C, Kitajima E W, Kormelink R, Goldbach R, Peters D
Abstract excerpt
During a series of mechanical transfers of tomato spotted wilt virus, two distinct types of mutants were generated. Firstly, a morphologically defective isolate was obtained which had lost the ability to produce the membrane glycoproteins and, as a consequence, was not able to form enveloped particles. Analysis of the genomic RNAs of this isolate suggested that this defect was caused by either point mutations or...
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