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Article

Specific gene expression profiles and chromosomal abnormalities are associated with infant disseminated neuroblastoma

3 Feb 2009

Abstract excerpt

BACKGROUND: Neuroblastoma (NB) tumours have the highest incidence of spontaneous remission, especially among the stage 4s NB subgroup affecting infants. Clinical distinction of stage 4s from lethal stage 4 can be difficult, but critical for therapeutic decisions. The aim of this study was to investigate chromosomal alterations and differential gene expression amongst infant disseminated NB subgroups. METHODS:...

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PMID: 19192278
DOI: 10.1186/1471-2407-9-44

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