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Article

An activating beta1 integrin mutation increases the conversion of benign to malignant skin tumors.

Cancer research - 15 Feb 2009

Ferreira Manuela, Fujiwara Hironobu, Morita Kazumasa, Watt Fiona M

Abstract excerpt

Identifying the physiologic relevance of cancer-associated genetic polymorphisms is a major challenge. Several changes in the coding sequence of beta integrin subunits have now been described in human tumors. One of these, T188Ibeta1, was identified as a heterozygous mutation in a poorly differen...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19190332
DOI: 10.1158/0008-5472.CAN-08-3051
PMCID: PMC2644725

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19190332-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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