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Article

Automatic detection of preclinical neurodegeneration

2 Feb 2009

Abstract excerpt

BACKGROUND: Treatment of neurodegenerative diseases is likely to be most beneficial in the very early, possibly preclinical stages of degeneration. We explored the usefulness of fully automatic structural MRI classification methods for detecting subtle degenerative change. The availability of a definitive genetic test for Huntington disease (HD) provides an excellent metric for judging the performance of such...

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PMID: 19188573
DOI: 10.1212/01.wnl.0000341768.28646.b6

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