Article
Analysis of Vitamin D Receptor Polymorphisms in Patients with Familial Multiple Sclerosis.
Medical archives (Sarajevo, Bosnia and Herzegovina) - 1 Feb 2018
Yucel Fatma Ebru, Kamıslı Ozden, Acar Ceren, Sozen Mert, Tecellioğlu Mehmet, Ozcan Cemal
Abstract excerpt
OBJECTIVE: Genetic and environmental factors are important in the development of the multiple sclerosis (MS). Vitamin D shows its effects on the immune system with the vitamin D receptor (VDR) in the nucleus. Single nucleotide polymorphisms (SNPs) in the VDR gene can lead to alterations in vitamin D functions and metabolism.Taq I, Apa I, Fok I and Bsm I polymorphisms and MS associations have been investigated in...
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