Article
Carbon metabolism regulates expression of the pfl (pyruvate formate-lyase) gene in Escherichia coli.
Journal of bacteriology - 1 Oct 1991
Rasmussen L J, Møller P L, Atlung T
Abstract excerpt
The anaerobic expression of pfl is reduced both in a strain mutated in the pgi gene and in a pfkA pfkB double mutant strain when cells are grown in medium supplemented with glucose. When cells are grown in medium supplemented with either fructose or pyruvate, no reduction is observed in these strains. The amount of pyruvate in the cells may be responsible for the reduced expression of pfl in the strains mutated...
Topics
- Acetyltransferases
- Amino Acids
- DNA, Bacterial
- DNA, Superhelical
- Escherichia coli
- Fructose
- Gene Expression Regulation, Bacterial
- Glucose
- Kinetics
- Mutation
- Operon
- Osmolar Concentration