Article
A 5'-truncated c-myc gene variant not associated with a risk of cancer.
Human genetics - 1 Sept 1991
Pellegata N S, Bergamaschi G, Amadori D, Aloia A, Ballarini P, Del Senno L, Amaducci L, Ranzani G N
Abstract excerpt
By analyzing c-myc specific fragments from white blood cell DNAs of 98 gastric cancer patients and 46 control subjects, we observed 6 unexpected patterns due to presence of a variant c-myc gene in addition to the normal gene. Restriction enzyme mapping indicated that the variant c-myc gene was the result of a 5' deletion including the first exon and part of the first intron. The deleted region, non-coding for the...
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