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Article

Identification and association analysis of single nucleotide polymorphisms in the human noggin (NOG) gene and osteoporosis phenotypes.

Bone - 1 May 2009

Moffett Susan P, Dillon Katie A, Yerges Laura M, Goodrich Louis J, Nestlerode Cara, Bunker Clareann H, Wheeler Victor W, Patrick Alan L, Zmuda Joseph M

Abstract excerpt

Noggin, an extracellular bone morphogenic protein (BMP) antagonist, blocks BMP signaling and decreases osteoblastogenesis. The purpose of this study was to identify novel sequence variations in the human noggin gene and to perform association analyses of these variations with phenotypes related to osteoporosis. Novel single nucleotide polymorphisms (SNPs) were identified by resequencing 7 kb of the noggin gene...

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Source

Identifiers

PMID: 19167531
DOI: 10.1016/j.bone.2008.12.024

Genes

NOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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