Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of the deubiquitinating enzyme Ubp2 and the e3 ligase Rsp5 is required for transporter/receptor sorting in the multivesicular body pathway.

PloS one - 1 Jan 2009

Lam Mandy H Y, Urban-Grimal Danièle, Bugnicourt Amandine, Greenblatt Jack F, Haguenauer-Tsapis Rosine, Emili Andrew

Abstract excerpt

Protein ubiquitination is essential for many events linked to intracellular protein trafficking. We sought to elucidate the possible involvement of the S. cerevisiae deubiquitinating enzyme Ubp2 in transporter and receptor trafficking after we (this study) and others established that affinity purified Ubp2 interacts stably with the E3 ubiquitin ligase Rsp5 and the (ubiquitin associated) UBA domain containing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Catalysis
Share to Endocytosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endopeptidases

Share to Endosomal Sorting Complexes Required for Transport

Share to Fluorouracil

Share to Mating Factor

Share to Ubiquitin-Protein Ligase Complexes

Share to Ubiquitin-Protein Ligases

Source

Open in PubMed Open full text

Identifiers

PMID: 19165343
DOI: 10.1371/journal.pone.0004259
PMCID: PMC2626285

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of the deubiquitinating enzyme Ubp2 and the e3 ligase Rsp5 is required for transporter/receptor sorting in the multivesicular body pathway.PMID 19165343Read ↗

Localization of the Rsp5p ubiquitin-protein ligase at multiple sites within the endocytic pathway.Semantic proximity Read ↗

WW domains of Rsp5p define different functions: determination of roles in fluid phase and uracil permease endocytosis in Saccharomyces cerevisiae.Semantic proximity Read ↗

The C2 domain of the Rsp5 ubiquitin ligase binds membrane phosphoinositides and directs ubiquitination of endosomal cargo.Semantic proximity Read ↗

'ER degradation' of a mutant yeast plasma membrane protein by the ubiquitin-proteasome pathway.Semantic proximity Read ↗

Domains of the Rsp5 ubiquitin-protein ligase required for receptor-mediated and fluid-phase endocytosis.Semantic proximity Read ↗

The ubiquitin ligase Rsp5p is required for modification and sorting of membrane proteins into multivesicular bodies.Semantic proximity Read ↗

Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S.Semantic proximity Read ↗

Antagonistic roles of ESCRT and Vps class C/HOPS complexes in the recycling of yeast membrane proteins.Semantic proximity Read ↗

BsdA(Bsd2) -dependent vacuolar turnover of a misfolded version of the UapA transporter along the secretory pathway: prominent role of selective autophagy.Semantic proximity Read ↗

Targeting of Sna3p to the endosomal pathway depends on its interaction with Rsp5p and multivesicular body sorting on its ubiquitylation.Semantic proximity Read ↗

Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins.Semantic proximity Read ↗

Characterization of multiple multivesicular body sorting determinants within Sna3: a role for the ubiquitin ligase Rsp5.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.