Article
Improved oxygen diffusion and mechanical aggregation of tumor colonies in a novel stirred mini-bioreactor.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jan 2008
Thouas George A, Thompson Mark C, Contreras Karla G, Liow Keith Y S, Tan Kenny B T, Hourigan Keny
Abstract excerpt
The feasibility of a novel stirred bioreactor, the rotating aerial disk (RAD) design, was tested in this study. The novelty lies in its method of medium recirculation by convective airflow using a non-contact planar disc, a variation on a physically defined theoretical model. Computational predictions of improved oxygenation were confirmed by increases in measured dissolved oxygen, even at Reynolds numbers...
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