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Article

The crystal structure of C176A mutated [Fe]-hydrogenase suggests an acyl-iron ligation in the active site iron complex.

FEBS letters - 4 Feb 2009

Hiromoto Takeshi, Ataka Kenichi, Pilak Oliver, Vogt Sonja, Stagni Marco Salomone, Meyer-Klaucke Wolfram, Warkentin Eberhard, Thauer Rudolf K, Shima Seigo, Ermler Ulrich

Abstract excerpt

[Fe]-hydrogenase is one of three types of enzymes known to activate H(2). Crystal structure analysis recently revealed that its active site iron is ligated square-pyramidally by Cys176-sulfur, two CO, an "unknown" ligand and the sp(2)-hybridized nitrogen of a unique iron-guanylylpyridinol-cofacto...

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Identifiers

PMID: 19162018
DOI: 10.1016/j.febslet.2009.01.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19162018-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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