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Article

Phosphorylation of survivin at threonine 34 inhibits its mitotic function and enhances its cytoprotective activity.

Cell cycle (Georgetown, Tex.) - 15 Jan 2009

Barrett Rachel M A, Osborne Toby P, Wheatley Sally P

Abstract excerpt

Survivin is an essential chromosomal passenger protein required for mitotic progression. It is also an inhibitor of apoptosis and can prevent caspase-mediated cell death. In addition, survivin levels are elevated in cancer cells where its presence correlates with increased resistance to chemo- an...

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Identifiers

PMID: 19158485
DOI: 10.4161/cc.8.2.7587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19158485-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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