Article
The evolution of Epstein-Barr virus inferred from the conservation and mutation of the virus glycoprotein gp350/220 gene.
Virus genes - 1 Apr 2009
Kawaguchi Asako, Kanai Kyosuke, Satoh Yukio, Touge Chizu, Nagata Keiko, Sairenji Takeshi, Inoue Yoshitsugu
Abstract excerpt
To study variations of Epstein-Barr virus (EBV), we analyzed the gp350/220 gene for several cell lines and Japanese wild isolates using direct sequencing. The N-terminal region was highly conserved in all EBVs except for Jijoye/P3HR-1 and a few isolates. The variation of the region coincided with EBV types A and B (also referred to as types 1 and 2) and were, respectively, designated as the types a and b. The...
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