Article
Role of stem cell factor and bone marrow-derived fibroblasts in airway remodeling.
The American journal of pathology - 1 Feb 2009
Dolgachev Vladislav A, Ullenbruch Matthew R, Lukacs Nicholas W, Phan Sem H
Abstract excerpt
Recent evidence suggests that bone marrow-derived fibroblasts are involved in airway remodeling in asthma, but the role and mechanism of recruitment of these fibroblasts remains unclear. Stem cell factor (SCF), a key factor in the propagation of hematopoietic stem cells, is important in the process of airway remodeling as well. To test the hypothesis that SCF is involved in the recruitment and differentiation of...
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