Article
High frequency of rifampin resistance identified in an epidemic Clostridium difficile clone from a large teaching hospital.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Feb 2009
Curry Scott R, Marsh Jane W, Shutt Kathleen A, Muto Carlene A, O'Leary Mary M, Saul Melissa I, Pasculle A William, Harrison Lee H
Abstract excerpt
BACKGROUND: Rifampin is used as adjunctive therapy for Clostridium difficile-associated disease, and the drug's derivative, rifaximin, has emerged as an attractive antimicrobial for treatment of C. difficile-associated disease. Rifampin resistance in C. difficile strains has been reported to be uncommon. METHODS: We examined the prevalence of rifampin resistance among 470 C. difficile isolates (51.1% during...
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