Article
Formycin A resistant mutants due to defect in adenosine transport system in Vibrio parahaemolyticus.
Chemical & pharmaceutical bulletin - 1 May 1991
Sakai-Tomita Y, Mitani Y, Tsuda M, Tsuchiya T
Abstract excerpt
An antibiotic formycin A inhibited growth of Vibrio parahaemolyticus under certain conditions, which suggested that formycin A was taken up by cells under these conditions. We found that formycin A was transported via the adenosine transport system which we previously reported as a Na(+)-coupled cotransport system. We isolated many formycin A resistant mutants, and about half of them grew very poorly on adenosine...
Topics
- Adenosine
- Biological Transport, Active
- Drug Resistance, Microbial
- Formycins
- Mutation
- Vibrio parahaemolyticus