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Article

The<i>ex vivo</i>response of human intestinal mucosa to enteropathogenic<i>Escherichia coli</i>infection

11 Dec 2008

Abstract excerpt

In vitro organ culture (IVOC) represents a gold standard model to study enteropathogenic E. coli (EPEC) infection of human intestinal mucosa. However, the optimal examination of the bacterial-host cell interaction requires a directional epithelial exposure, without serosal or cut surface stimulation. A polarized IVOC system (pIVOC) was developed in order to overcome such limitations: apical EPEC infection...

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PMID: 19134113
DOI: 10.1111/j.1462-5822.2008.01275.x

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