Article
Association of insertion/deletion polymorphism of angiotensin-converting enzyme gene with essential hypertension and type 2 diabetes mellitus in Malaysian subjects.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2008
Ramachandran Vasudevan, Ismail Patimah, Stanslas Johnson, Shamsudin Norashikin, Moin Saidi, Mohd Jas Rusni
Abstract excerpt
INTRODUCTION: The deletion (D) allele of the angiotensin-converting enzyme (ACE) gene has been studied in various populations in relation to hypertension (HTN) and type 2 diabetes mellitus (T2DM) with contradictory results. This study sought to determine the association of insertion (I)/D polymorphism of the ACE gene in hypertensive and T2DM subjects in a Malaysian population. MATERIALS AND METHODS: A total of...
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