Article
Distribution of HIV-1 resistant polymorphisms among HIV infected patients in Georgia.
Georgian medical news - 1 Dec 2008
Karchava M, Nelson Kenrad E, Gochitashvili N, Dvali N, Tsertsvadze T
Abstract excerpt
Host genetic factors are believed to play an important role in the pathogenesis and natural history of HIV disease along with determining the rate and severity of HIV epidemic in a particular country. CCR5, CCR2 and SDF1 genes are known to influence the susceptibility to HIV-1 infection and to be involved in the rate of disease progression. Unlike CCR5 Delta32 mutation, mutations in CCR2-64I and SDF1-3A do not...
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