Article
Distribution of CCR5delta32, CCR2-64I and SDF1-3'A and plasma levels of SDF-1 in HIV-1 seronegative North Indians.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Mar 2007
Verma Romsha, Gupta Radha Ballabh, Singh Kalpana, Bhasin Rama, Anand Shukla Abhay, Chauhan Shyam S, Luthra Kalpana
Abstract excerpt
Host genetic factors play an important role in susceptibility to HIV-1 infection and progression to AIDS. Mutations in genes encoding chemokine receptors and their ligands, viz., CCR5delta32, CCR2-64I and SDF1-3'A are implicated to have protective effects against HIV-1 infection and/or disease progression. The distribution of these gene polymorphisms and their role in the course of the disease varies between...
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