Article
Recombination between vaccine and field strains of canine parvovirus is revealed by isolation of virus in canine and feline cell cultures.
The Journal of veterinary medical science - 1 Dec 2008
Mochizuki Masami, Ohshima Takahisa, Une Yumi, Yachi Akiko
Abstract excerpt
Canine parvovirus type 2 (CPV) is a pathogen that causes severe hemorrhagic gastroenteritis with a high fatality rate in pups worldwide. Since CPV emerged in the late 1970s, its origin has been explored with the conclusion that CPV originated from feline panleukopenia virus or a closely related virus. Both high mutation rate and recombination are assumed to be key factors in the evolution of parvoviruses. Here we...
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