Article
From Type 1, through LADA, to type 2 diabetes: a continuous spectrum?
Annals of the New York Academy of Sciences - 1 Dec 2008
Lin J, Zhou Z G, Wang J P, Zhang C, Huang G
Abstract excerpt
This study aims to explore whether diabetes mellitus from T1DM, through LADA, to T2DM presents a continuous spectrum in terms of HLA-DQ genetic background. We recruited 223 patients with autoimmune T1DM, 215 with LADA, 206 with T2DM, and 228 nondiabetic controls, and then defined their HLA-DQA1 and -DQB1 genotypes and haplotypes. T1DM patients were divided into two groups depending on age of onset of disease:...
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