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Article

Low-level copy gain versus amplification of myc oncogenes in medulloblastoma: utility in predicting prognosis and survival. Laboratory investigation.

Journal of neurosurgery. Pediatrics - 1 Jan 2009

Takei Hidehiro, Nguyen Yummy, Mehta Vidya, Chintagumpala Murali, Dauser Robert C, Adesina Adekunle M

Abstract excerpt

OBJECT: Medulloblastoma (MB) is a malignant embryonal tumor of the cerebellum. Amplification of c-myc or N-myc is infrequently identified and, when present, is often associated with the large cell/anaplastic (LC/A) phenotype. The frequency of low-level copy gain of myc oncogenes and its relationship to prognosis of MB has not been explored. METHODS: Archival cases of MB were histologically reviewed and classified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19119907
DOI: 10.3171/2008.10.PEDS08105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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