Article
The effect of an exon 12 polymorphism of the human thromboxane synthase (CYP5A1) gene in stroke patients.
Medical science monitor : international medical journal of experimental and clinical research - 1 Jan 2009
Kimouli Maria, Gourvas Viktoras, Konstantoudaki Xanthippi, Basta Maria, Miyakis Spiros, Spandidos Demetrios A
Abstract excerpt
BACKGROUND: To examine the prevalence of an exon 12 polymorphism on the human Thromboxane synthase (CYP5A1) gene. MATERIAL/METHODS: Using sequence-specific PCR, we examined the allelic prevalence in 237 Greek patients with ischemic strokes and in 171 controls. In addition, we compared the CYP5A1 allelic prevalence in 71 patients with stroke recurrence despite Aspirin use, in comparison with patients who have not...
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