Article
BolA inhibits cell elongation and regulates MreB expression levels.
Journal of molecular biology - 6 Feb 2009
Freire Patrick, Moreira Ricardo Neves, Arraiano Cecília Maria
Abstract excerpt
The morphogene bolA is a general stress response gene in Escherichia coli that induces a round morphology when overexpressed. Results presented in this report show that increased BolA levels can inhibit cell elongation mechanisms. MreB polymerization is crucial for the bacterial cell cytoskeleton, and this protein is essential for the maintenance of a cellular rod shape. In this report, we demonstrate that bolA...
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