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Article

Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study.

Lancet (London, England) - 24 Jan 2009

Collet Jean-Philippe, Hulot Jean-Sébastien, Pena Anna, Villard Eric, Esteve Jean-Baptiste, Silvain Johanne, Payot Laurent, Brugier Delphine, Cayla Guillaume, Beygui Farzin, Bensimon Gilbert, Funck-Brentano Christian, Montalescot Gilles

Abstract excerpt

BACKGROUND: Clopidogrel and low-dose aspirin have become the mainstay oral antiplatelet regimen to prevent recurrent ischaemic events after acute coronary syndromes or stent placement. The frequent genetic functional variant 681 G>A (*2) of cytochrome P450 2C19 (CYP2C19) is an important contributor to the wide variability between individuals of the antiplatelet effect of clopidogrel. We assessed whether the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19108880
DOI: 10.1016/S0140-6736(08)61845-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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