Article
Dyskerin, telomerase and the DNA damage response.
Cell cycle (Georgetown, Tex.) - 1 Jan 2009
Gu BaiWei, Bessler Monica, Mason Philip J
Abstract excerpt
The bone marrow failure syndrome Dyskeratosis congenita (DC), though rare, has attracted a great deal of attention in the last few years because it is caused by mutations in genes whose products are involved in telomere maintenance. The disease presents with a variety of features that can all be due to failure of tissues that require constant renewal via stem cell activity. It is thought this is caused by defects...
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