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Article

Shwachman-Diamond syndrome: implications for understanding the molecular basis of leukaemia.

Expert reviews in molecular medicine - 23 Dec 2008

Dror Yigal

Abstract excerpt

Inherited bone marrow failure syndromes provide extremely useful genetic models for understanding leukaemogenesis because the initial genetic defect can be identified and the risk of leukaemia is very high. Shwachman-Diamond syndrome is one of the most common inherited bone marrow failure syndromes and an example of such a model. Here, I describe the malignant features of Shwachman-Diamond syndrome and discuss...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19102804
DOI: 10.1017/S1462399408000938

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