Article
[Detection of gene mutations of SCN5A in 7 patients with Brugada syndrome].
Zhonghua xin xue guan bing za zhi - 1 May 2008
Yuan Bin-bin, Shan Qi-jun, Yang Bing, Chen Ming-long, Zou Jian-gang, Chen Chun, Xu Dong-jie, Cao Ke-jiang
Abstract excerpt
OBJECTIVE: Brugada syndrome is linked to sodium channel mutations and could induce arrhythmias that even lead to sudden death. The purpose of this study was to detect if there was gene mutation of SCN5A in 7 patients with Brugada syndrome and explore the molecular genetic characteristics of this disease. METHOD: Genomic DNA was extracted from peripheral blood of all 7 patients with Brugada syndrome and 41 pairs...
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