Article
The refractive state of the eye in Icelandic horses with the Silver mutation.
BMC veterinary research - 2 Jun 2017
Johansson Maria K, Jäderkvist Fegraeus Kim, Lindgren Gabriella, Ekesten Björn
Abstract excerpt
BACKGROUND: The syndrome Multiple Congenital Ocular Anomalies (MCOA) is a congenital eye disorder in horses. Both the MCOA syndrome and the Silver coat colour in horses are caused by the same missense mutation in the premelanosome protein (PMEL) gene. Horses homozygous for the Silver mutation (TT) are affected by multiple ocular defects causing visual impairment or blindness. Horses heterozygous for the Silver...
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