Article
Effects of polymorphism of the beta(1) adrenoreceptor and CYP2D6 on the therapeutic effects of metoprolol.
The Journal of international medical research - 1 Jan 2000
Yuan H, Huang Z, Yang G, Lv H, Sang H, Yao Y
Abstract excerpt
Metoprolol is a lipophilic beta(1) selective adrenergic receptor antagonist used in antihypertensive therapy. It is metabolized by the protein product of the cytochrome P450 2D6 (CYP2D6) gene. Few studies have been performed on the association between the beta(1) adrenoreceptor, CYP2D6 polymorphi...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
