Article
[Association of -6735T-->C variant of glucokinase-associated dual-specificity phosphatase 12 gene with type 2 diabetes in Chinese].
Zhonghua yi xue za zhi - 19 Aug 2008
Gao Fei, Zhang Rong, Hu Cheng, Fang Qi-chen, Wang Cong-rong, Ma Xiao-jing, Lu Jun-xi, Xu Jing, Jia Wei-ping, Xiang Kun-san
Abstract excerpt
OBJECTIVE: To investigate the impact of glucokinase-associated dual-specificity phosphatase 12 gene (DUSP12) single nucleotide polymorphism (SNP) on type 2 diabetes mellitus in Chinese. METHODS: The genotypes of -6735T-->C of DUSP12 were determined by PCR-RFLP in 577 Chinese in Shanghai, 359 with normal glucose tolerance (NGT) and 218 being newly diagnosed DM patients without taking any drug. Oral glucose...
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