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Article

Characterization of the molecular phenotype of two arrhythmogenic right ventricular cardiomyopathy (ARVC)-related plakophilin-2 (PKP2) mutations.

Heart rhythm - 1 Dec 2008

Joshi-Mukherjee Rosy, Coombs Wanda, Musa Hassan, Oxford Eva, Taffet Steven, Delmar Mario

Abstract excerpt

BACKGROUND: Arrhythmogenic right ventricular cardiomyopathy (ARVC) has been linked to mutations in desmosomal proteins, including plakophilin-2 (PKP2). Little is known about the changes in cellular function and structure that follow expression of ARVC-relevant PKP2 mutations. OBJECTIVE: The purpo...

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Source

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Identifiers

PMID: 19084810
DOI: 10.1016/j.hrthm.2008.09.009
PMCID: PMC2636742

Genes

PKP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19084810-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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