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Article

Clinical features of arrhythmogenic right ventricular dysplasia/cardiomyopathy associated with mutations in plakophilin-2.

Circulation - 4 Apr 2006

Dalal Darshan, Molin Lorraine H, Piccini Jonathan, Tichnell Crystal, James Cynthia, Bomma Chandra, Prakasa Kalpana, Towbin Jeffrey A, Marcus Frank I, Spevak Philip J, Bluemke David A, Abraham Theodore, Russell Stuart D, Calkins Hugh, Judge Daniel P

Abstract excerpt

BACKGROUND: Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy characterized by right ventricular dysfunction and ventricular arrhythmias. A recent study reported mutations in PKP2, encoding the desmosomal protein plakophilin-2, associated with ARVD/...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16549640
DOI: 10.1161/CIRCULATIONAHA.105.568642

Genes

PKP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16549640-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Clinical features of arrhythmogenic right ventricular dysplasia/cardiomyopathy associated with mutations in plakophilin-2.PMID 16549640Read ↗

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Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.Semantic proximity Read ↗

Clinical and genetic characterization of patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy caused by a plakophilin-2 splice mutation.Semantic proximity Read ↗

Plakophilin-2 missense mutations in arrhythmogenic right ventricular cardiomyopathy.Semantic proximity Read ↗

Pathogenic variants in plakophilin-2 gene (PKP2) are associated with better survival in arrhythmogenic right ventricular cardiomyopathy.Semantic proximity Read ↗

Mutations of plakophilin-2 in Chinese with arrhythmogenic right ventricular dysplasia/cardiomyopathy.Semantic proximity Read ↗

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