Article
Vinculin is essential for muscle function in the nematode.
The Journal of cell biology - 1 Aug 1991
Barstead R J, Waterston R H
Abstract excerpt
Actin filaments in the body wall muscle of the nematode Caenorhabditis elegans are attached to the sarcolemma through vinculin-containing structures called dense bodies, Z-line analogues. To investigate the in vivo function of vinculin, we executed a genetic screen designed to recover mutations i...
Topics
- Animals
- Caenorhabditis
- Chromosome Mapping
- Crosses, Genetic
- Cytoskeletal Proteins
- DNA
- Embryo, Nonmammalian
- Female
- Genetic Complementation Test
- Genetic Linkage
- Male
- Muscles
- Mutation
- Nucleic Acid Heteroduplexes
- Transformation, Genetic
- Vinculin