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Article

Vinculin is essential for muscle function in the nematode.

The Journal of cell biology - 1 Aug 1991

Barstead R J, Waterston R H

Abstract excerpt

Actin filaments in the body wall muscle of the nematode Caenorhabditis elegans are attached to the sarcolemma through vinculin-containing structures called dense bodies, Z-line analogues. To investigate the in vivo function of vinculin, we executed a genetic screen designed to recover mutations in the region of the nematode vinculin gene, deb-1. According to four independent criteria, two of the isolated mutants...

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Identifiers

PMID: 1907975
DOI: 10.1083/jcb.114.4.715
PMCID: PMC2289884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Vinculin is essential for muscle function in the nematode.PMID 1907975Read ↗

Vinculin gene is non-essential in Drosophila melanogaster.Semantic proximity Read ↗

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Genes critical for muscle development and function in Caenorhabditis elegans identified through lethal mutations.Semantic proximity Read ↗

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