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Article

Improper adjustment for baseline in genetic association studies of change in phenotype.

Human heredity - 1 Jan 2009

McArdle P F, Whitcomb B W

Abstract excerpt

OBJECTIVE: In studies of associations between genetic factors and outcomes where change in phenotype is of interest, proper modeling of the data, particularly the treatment of baseline trait values, is required to draw valid conclusions. METHODS: The authors compared models of blood pressure response to a cold pressor test with and without inclusion of baseline blood pressure as a regressor and evaluate the...

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Identifiers

PMID: 19077436
DOI: 10.1159/000181156
PMCID: PMC2868920

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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