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Article

Intracellular amyloid beta-protein as a therapeutic target for treating Alzheimer's disease.

Current Alzheimer research - 1 Dec 2008

Ohyagi Y

Abstract excerpt

The amyloid cascade hypothesis is well known hypothesis describing the pathogenesis of Alzheimer's disease (AD). On the basis of this hypothesis, inhibition of amyloid beta-protein (Abeta) generation and aggregation, enhancement of extracellular Abeta removal, and Abeta vaccination are currently under investigation. Intracellular Abeta may be even more important than extracellular Abeta, since intraneuronal Abeta...

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PMID: 19075582
DOI: 10.2174/156720508786898514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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