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Simu-dependent clearance of dying cells regulates macrophage function and inflammation resolution

14 May 2019

Abstract excerpt

Macrophages encounter and clear apoptotic cells during normal development and homeostasis, including at numerous sites of pathology. Clearance of apoptotic cells has been intensively studied, but the effects of macrophage-apoptotic cell interactions on macrophage behaviour are poorly understood. Using Drosophila embryos, we have exploited the ease of manipulating cell death and apoptotic cell clearance in this...

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PMID: 31086359
DOI: 10.1371/journal.pbio.2006741

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