Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PTH(1-34) replacement therapy in a child with hypoparathyroidism caused by a sporadic calcium receptor mutation.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 May 2009

Theman Todd A, Collins Michael T, Dempster David W, Zhou Hua, Reynolds James C, Brahim Jaime S, Roschger Paul, Klaushofer Klaus, Winer Karen K

Abstract excerpt

Autosomal dominant hypocalcemia (ADH) is an inherited form of hypoparathyroidism caused by activating mutations in the calcium-sensing receptor (CaR). Treatment with PTH(1-34) may be superior to conventional therapy but is contraindicated in children, and long-term effects on the skeleton are unknown. The patient is a 20-yr-old female with ADH treated with PTH continuously since 6 yr and 2 mo of age. A bone...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Density
Share to Densitometry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hormone Replacement Therapy

Share to Hypoparathyroidism

Share to Parathyroid Hormone

Share to Receptors, Calcium-Sensing

Share to Tomography, X-Ray Computed

Source

Open in PubMed Open full text

Identifiers

PMID: 19063686
DOI: 10.1359/jbmr.081233
PMCID: PMC2672210

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PTH(1-34) replacement therapy in a child with hypoparathyroidism caused by a sporadic calcium receptor mutation.PMID 19063686Read ↗

Hypercalcemia in children and adolescents.Semantic proximity Read ↗

Recombinant human parathyroid hormone therapy (1-34) in an adult patient with a gain-of-function mutation in the calcium-sensing receptor-a case report.Semantic proximity Read ↗

Calcilytic Ameliorates Abnormalities of Mutant Calcium-Sensing Receptor (CaSR) Knock-In Mice Mimicking Autosomal Dominant Hypocalcemia (ADH).Semantic proximity Read ↗

Functional activities of mutant calcium-sensing receptors determine clinical presentations in patients with autosomal dominant hypocalcemia.Semantic proximity Read ↗

The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone.Semantic proximity Read ↗

Effect of parathyroid hormone administration in a patient with severe hypoparathyroidism caused by gain-of-function mutation of calcium-sensing receptor.Semantic proximity Read ↗

Progression of Mineral Ion Abnormalities in Patients With Jansen Metaphyseal Chondrodysplasia.Semantic proximity Read ↗

Skeletal consequences of familial hypocalciuric hypercalcaemia vs. primary hyperparathyroidism.Semantic proximity Read ↗

Sporadic hypoparathyroidism caused by de Novo gain-of-function mutations of the Ca(2+)-sensing receptor.Semantic proximity Read ↗

Comparison of hypocalcemic hypercalciuria between patients with idiopathic hypoparathyroidism and those with gain-of-function mutations in the calcium-sensing receptor: is it possible to differentiate the two disorders?Semantic proximity Read ↗

Normal bone mass and normocalcemia in adulthood despite homozygous vitamin D receptor mutations.Semantic proximity Read ↗

Phenotypic variation in a large family with autosomal dominant hypocalcaemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.