Article
Relation between human vasopressin 1a gene variance, fat intake, and diabetes.
The American journal of clinical nutrition - 1 Jan 2009
Enhörning Sofia, Leosdottir Margret, Wallström Peter, Gullberg Bo, Berglund Göran, Wirfält Elisabet, Melander Olle
Abstract excerpt
BACKGROUND: Male arginine vasopressin 1a receptor knockout mice (V1aR(-/-)) display a phenotype of low triglycerides and high glucose concentrations and high-fat-diet-induced obesity and diabetes. OBJECTIVE: We investigated whether genetic variation of the human arginine vasopressin 1A (AVPR1A) gene is associated with phenotypic features resembling those of the V1aR(-/-) mouse. DESIGN: In a population-based...
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