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Mutation of mitochondrial DNA G13513A presenting with Leigh syndrome, Wolff-Parkinson-White syndrome and cardiomyopathy.

Pediatrics and neonatology - 1 Aug 2008

Wang Shi-Bing, Weng Wen-Chin, Lee Ni-Chung, Hwu Wuh-Liang, Fan Pi-Chuan, Lee Wang-Tso

Abstract excerpt

Mutation of mitochondrial DNA (mtDNA) G13513A, encoding the ND5 subunit of respiratory chain complex I, can cause mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) and Leigh syndrome. Wolff-Parkinson-White (WPW) syndrome and optic atrophy were reported in a high proportion of patients with this mutation. We report an 18-month-old girl, with an 11-month history of psychomotor...

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PMID: 19054921
DOI: 10.1016/S1875-9572(08)60030-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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