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Article

The G13513A mutation in the ND5 gene of mitochondrial DNA as a common cause of MELAS or Leigh syndrome: evidence from 12 cases.

Archives of neurology - 1 Mar 2008

Shanske Sara, Coku Jorida, Lu Jiesheng, Ganesh Jaya, Krishna Sindu, Tanji Kurenai, Bonilla Eduardo, Naini Ali B, Hirano Michio, DiMauro Salvatore

Abstract excerpt

BACKGROUND: The number of molecular causes of MELAS (a syndrome consisting of mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes) and Leigh syndrome (LS) has steadily increased. Among these, mutations in the ND5 gene (OMIM 516005) of mitochondrial DNA are important, and the...

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PMID: 18332249
DOI: 10.1001/archneurol.2007.67

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18332249-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The G13513A mutation in the ND5 gene of mitochondrial DNA as a common cause of MELAS or Leigh syndrome: evidence from 12 cases.PMID 18332249Read ↗

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