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Article

Leigh disease with mitochondrial DNA A8344G mutation: case report and brief review.

Journal of child neurology - 1 Jan 2003

Tsao Chang-Yong, Herman Gail, Boué Daniel R, Prior Thomas W, Lo Warren D, Atkin Joan F, Rusin Jerome

Abstract excerpt

Leigh disease, subacute necrotizing encephalomyelopathy, is a neurodegenerative disorder often seen in infancy or childhood but rarely reported in adults. Genetic heterogeneity is well recognized, and the associated etiologies include both mitochondrial and nuclear DNA defects. We describe an infant presenting with developmental delay and then progressive multisystem disorder and neuroradiologic features of Leigh...

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Identifiers

PMID: 12661941
DOI: 10.1177/08830738030180011401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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