Article
Genomic complexity of the variable region-containing chitin-binding proteins in amphioxus.
BMC genetics - 1 Dec 2008
Dishaw Larry J, Mueller M Gail, Gwatney Natasha, Cannon John P, Haire Robert N, Litman Ronda T, Amemiya Chris T, Ota Tatsuya, Rowen Lee, Glusman Gustavo, Litman Gary W
Abstract excerpt
BACKGROUND: The variable region-containing chitin-binding proteins (VCBPs) are found in protochordates and consist of two tandem immunoglobulin variable (V)-type domains and a chitin-binding domain. We previously have shown that these polymorphic genes, which primarily are expressed in the gut, exhibit characteristics of immune genes. In this report, we describe VCBP genomic organization and characterize adjacent...
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