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Article

A family of variable immunoglobulin and lectin domain containing molecules in the snail Biomphalaria glabrata.

Developmental and comparative immunology - 1 Jan 2015

Dheilly Nolwenn M, Duval David, Mouahid Gabriel, Emans Rémi, Allienne Jean-François, Galinier Richard, Genthon Clémence, Dubois Emeric, Du Pasquier Louis, Adema Coen M, Grunau Christoph, Mitta Guillaume, Gourbal Benjamin

Abstract excerpt

Technical limitations have hindered comprehensive studies of highly variable immune response molecules that are thought to have evolved due to pathogen-mediated selection such as fibrinogen-related proteins (FREPs) from Biomphalaria glabrata. FREPs combine upstream immunoglobulin superfamily (IgSF) domains with a C-terminal fibrinogen-related domain (FreD) and participate in reactions against trematode parasites....

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Identifiers

PMID: 25451302
DOI: 10.1016/j.dci.2014.10.009
PMCID: PMC4255472

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