Article
[Familial hypercholesterolemia in Tunisia].
Pathologie-biologie - 1 Jul 2009
Jelassi A, Jguirim I, Najah M, Maatouk F, Ben Hamda K, Slimane M N
Abstract excerpt
Familial hypercholesterolemia or autosomal dominant hypercholesterolemia is characterized by raised serum LDL (low density lipoproteins)-cholesterol levels, which result in excess deposition of cholesterol in tissues, leading to accelerated atherosclerosis and increased risk of premature coronary heart disease. Familial hypercholesterolemia results from defects in the hepatic uptake and degradation of LDL via the...
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