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Article

Human genetic selection on the MTHFR 677C>T polymorphism.

BMC medical genetics - 28 Nov 2008

Mayor-Olea Alvaro, Callejón Gonzalo, Palomares Arturo R, Jiménez Ana J, Gaitán María Jesús, Rodríguez Alfonso, Ruiz Maximiliano, Reyes-Engel Armando

Abstract excerpt

BACKGROUND: The prevalence of genotypes of the 677C>T polymorphism for the MTHFR gene varies among humans. In previous studies, we found changes in the genotypic frequencies of this polymorphism in populations of different ages, suggesting that this could be caused by an increase in the intake of folate and multivitamins by women during the periconceptional period. The aim was to analyze changes in the allelic...

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Source

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Identifiers

PMID: 19040733
DOI: 10.1186/1471-2350-9-104
PMCID: PMC2610030

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Human genetic selection on the MTHFR 677C>T polymorphism.PMID 19040733Read ↗

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